#profound

He that knows himself, knows others; and he that is ignorant of himself, could not write a very profound lecture on other men's heads. ↗

— Charles Caleb Colton

#heads #himself #ignorant #knows #lecture

After all, the chief business of the American people is business. They are profoundly concerned with producing, buying, selling, investing and prospering in the world. ↗

— Calvin Coolidge

#american #american people #business #buying #chief

Our observation of nature must be diligent, our reflection profound, and our experiments exact. We rarely see these three means combined; and for this reason, creative geniuses are not common. ↗

— Denis Diderot

#common #creative #diligent #exact #experiments

That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin. ↗

— Edward Lawrie Tatum

#amino #amino acid #another #been #changes

I can't pick out one single book that had such a profound personal impact. ↗

— Louise Brown

#had #i #impact #out #personal

The most profound things are inexpressible. ↗

— Jenny Holzer

#most #profound #things

There's something about sitting alone in the dark that reminds you how big the world really is, and how far apart we all are. ↗

— Kami Garcia

#thoughts #truth #beauty

I have to tell you, though, the sexism in late night talk is so profound. ↗