The '80s were a time of technical wonder in filmmaking; unfortunately, some colleges didn't integrate their film and theater departments - so you had actors who were afraid of the camera, and directors who couldn't talk to the actors. ↗
You might make a lot of money, but it's very hard to get out from under that rug. The more you can reinvent yourself, the better - and unfortunately TV is designed not to let you redesign yourself. ↗
Unfortunately, in some parts of the country, some kids are taught at an early age that being different is somehow bad or wrong or worthy of ridicule. ↗
The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority. ↗