#lem

A key issue in developmental biology at that time was the problem of how cells underwent differentiation, with most workers concentrating on explanations in terms of changes in enzyme and gene regulation. ↗

— Paul Nurse

#cells #changes #concentrating #developmental #differentiation

I felt strongly that since the pursuit of good science was so difficult it was essential that the problem being studied was an important one to justify the effort expanded. ↗

— Paul Nurse

#difficult #effort #essential #expanded #felt

When we see the shadow on our images, are we seeing the time 11 minutes ago on Mars? Or are we seeing the time on Mars as observed from Earth now? It's like time travel problems in science fiction. When is now; when was then? ↗

— Bill Nye

#earth #fiction #images #like #mars

I'm not saying that there weren't other inherent problems with the score that couldn't have been overcome with a bit of remixing, but why did they ask me to do it, and why did Griffin ask me to do it this way, for a film that had nothing to do with American vernacular? ↗

— Michael Nyman

#ask #been #bit #did #film

If life gives you lemons, make some kind of fruity juice. ↗

— Conan O'Brien

#juice #kind #lemons #life #make

The writer operates at a peculiar crossroads where time and place and eternity somehow meet. His problem is to find that location. ↗

— Flannery O'Connor

#eternity #find #his #location #meet

The freedom to criticize judges and other public officials is necessary to a vibrant democracy. The problem comes when healthy criticism is replaced with more destructive intimidation and sanctions. ↗

— Sandra Day O'Connor

#criticism #criticize #democracy #destructive #freedom

What was a problem was the excessive amount of media attention to the appointment of the first woman and everything she did. Everywhere that Sandra went, the press was sure to go. And that got tiresome; it was stressful. ↗

— Sandra Day O'Connor

#appointment #attention #did #everything #everywhere

I don't do anything in order to cause trouble. It just so happens that what I do naturally causes trouble. I'm proud to be a troublemaker. ↗

— Sinead O'Connor

#cause #causes #happens #i #i do

They just have a feel about them. And you feel your way through them and you come out with something that's very powerful and mythic. And you don't quite know how you got there. I think this story has a lot of those elements. ↗

— Michael O'Donoghue

#come #elements #feel #got #how