Directors are not worried about casting beautiful women, but they are not sure that they want to cast great-looking men. My looks have prevented people from seeing my work.

Philanthropy
Lowe was the first male spokesperson for the 2000 Lee National Denim Day fundraiser which raises millions of dollars for breast cancer research and education. The couple have two sons: Erick Matthew Lowe (b. In an episode broadcast on May 16 2010 his character was part of a multi-vehicle crash involving a large truck and was put into a coma the storyline was wrapped up in the first episode of the fifth season; Lowe did not appear in the episode.

On television he played Sam Seaborn on The West Wing and Senator Robert McCallister on Brothers & Sisters. St.