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He had two daughters with his third wife Betty Bartholomew. His granddaughter is singer-songwriter Samantha James. Rose also worked as a standby pianist for NBC Radio.

In addition Rose was musical director for The Red Skelton Show during its 21-year-run on the CBS and NBC networks. He also wrote music for many television series including It's a Great Life The Tony Martin Show Little House on the Prairie Highway To Heaven Bonanza and Highway Patrol under the pseudonym "Ray Llewellyn.