You know, being an entertainer is partly being on the road, and a lot of your songs come from the road.

He wrote the hits "I Ain't Never" (Tillis's own future hit) and "Crazy Wild Desire". Still later he operated WMML in Mobile Alabama. He is also known for his speech impediment which does not affect his singing voice.

Tillis's biggest hits include "I Ain't Never" "Good Woman Blues" and "Coca-Cola Cowboy". Although he recorded songs since the late 1950s his biggest success occurred in the 1970s with a long list of Top 10 hits.