Who but the sports-mad [Norman] Mailer would liken the battle between God and the Devil to a game of American football? The contest, for sure, has with [sic] own laws (so that after God and the Devil 'tackle a guy, they don't kick him in the head'), but each side is not above cheating—with God breaking the rules occasionally by throwing in 'a miracle'. Strangely, Mailer doesn’t mention Jesus in this agonising analogy, but then the notion of the 'super-sub' may be an image too far even for him.

In November 2010 Hitchens cancelled a scheduled appearance in New York where he was to debate writers David Hazony and Stephen Prothero on the subject of the Ten Commandments. He also criticised Bush's support of intelligent design and capital punishment. He will tell it really well.

His anti-religion polemic God Is Not Great sold over 500000 copies. Hitchens died on 15 December 2011 from complications arising from oesophageal cancer a disease that he acknowledged was likely due to his lifelong predilection for heavy smoking and drinking.