I wanted to be an astronaut and wanted to go to space camp, but then I found out that I was too short to become an astronaut. My mom really made me believe that if I worked hard enough and if I really wanted to do it, I could do it.

Based on the board game of the same name Frye shared hosting duties with Sarah Michelle Gellar and Rod Brogan. Frye's parents divorced when Soleil Moon Frye was two. Frye was educated at a private school in Los Feliz and attended San Fernando Valley Professional School in Burbank.

She has since continued her acting career working mainly as a voice actor. In 2000 Soleil Moon Frye joined the cast of Sabrina the Teenage Witch as Roxie King Sabrina Spellman's (Melissa Joan Hart) roommate and close friend. Frye began her career as a child actor at the age of 2.